| 1 |
投稿者：Black Jack |
2006/04/22(Sat) |
| |
case181 |
| |
There are clusters of cells with clear cytoplasm
and thickened cell border near the vessels, together with scattered
eccrine ducts in the reticular dermis. Origin of these cells could
be of either eccrine, pericytic or histiocytic. Special staining
can help the differentiation. |
| |
|
|
| |
|
| 2 |
投稿者： 橘 充弘 |
2006/04/22(Sat) |
| |
Case181: Clear cell change due to glycogen
accumulation |
| |
グリコ−ゲンの沈着に伴う泡沫化で、決して、稀ではなく、時々見られます。PAS染色をしてみるとよいかも・・・病的意義はありません。 |
| |
|
|
| |
Case181: Clear cell change due to glycogen accumulation
投稿者：Black Jack |
2006/04/22(Sat) |
| |
Thank you. |
| |
|
| |
|
| 3 |
投稿者：大日輝記 |
2006/04/24(Mon) |
| |
Case 181: Mycobacterial infection |
| |
見たことのない組織像です。転移性腫瘍にしては異型が目立ちません。泡沫細胞というのでしょうか？明るい胞体を持った組織球様の細胞が血管周囲に浸潤しています。特異的な炎症像なのかどうかも分かりません。上記と考えました。 |
| |
|
| |
Re: Case 181: Mycobacterial infection
投稿者：Tetsunori Kimura |
2006/04//24(Mon) |
| |
I intepreted the pale cells around the blood vessels
as foam cells, i.e. xanthoma cells. |
| |
|
| |
|
| 4 |
投稿者：Tetsunori Kimura |
2006/04/24(Mon) |
| |
Case 181 |
| |
You can examine the details of pale cells by new image.
|
| |
|
| |
|
| 5 |
投稿者：KEIGO |
2006/04/24(Mon) |
| |
CASE181:Eruptive xanthoma |
| |
My diagnosis is eruptive xanthoma.
I can see foam cells around the vessels.
I think that the foam cell is lipid-laden histiocyte. |
| |
|
| |
|
| 5 |
投稿者：Black Jack |
2006/04/27(Thu) |
| |
Ccase181 review |
| |
If the clear cells are xanthoma cells, the simplest
answer is xanthelasma. Several different forms of xanthomata must
be differentiated. Eruptive xanthoma associated with hypertriglyceridemia
is unlikely because of the lack of extracellular lipid deposits as
usually found in this lesion. Normolipemic plane xanthoma frequently
associated with paraproteinemia is also unlikely because of the lack
of xanthogranulomatous features including Touton cells. Palmar xanthoma
with high IDL is difficult to identify because the location is not
described. Tuberous xanthoma with high LDL is unlikely because the
lesion is not tuberous and not associated with cholesterol crystals.
However, abortive lesions of the diseases as described might show
similar histology to the given images. Then, blood chemistry including
lipids and paraproteins must be investigated for the differential
diagnosis. |
| |
|